it sounds like you are considering taking the home off the long-term rental market? With many colleges around, there’s definitely a market for visiting parents, etc. although you will likely have to contend with slow-season drops when you will get very few rental requests (around holidays, possibly over the summer when students return home, etc). Universities almost always have hotels nearby for visiting lecturers, administrators, etc. but you will not likely get many of those bookings as they are usually made through official channels. If the universities are research-oriented, you have a shot at post-doc’s and visiting professors doing research but those people often have a limited budget so you may not be able to ask for much more than long-term monthly rates. Some students might be interested in short-term housing for summer courses or intensive language programs, etc. but you would want to check out what the cost of available student housing is.
So you may not make more money than you would with a long-term lease given seasonal lows but if you value having your place available for visiting friends and family, that may not be a bad thing.