When my husband was diagnosed with environmental allergies, we had to purchase hypoallergenic bedding. You are correct that all cotton bedding washed in regular detergent is not considered hypoallergenic. We got a dust mite proof mattress cover and got rid of our down quilt and pillows and replaced them with a quilt and pillows filled with hypoallergenic materials. We also got dust mite proof coverings for our pillows.