Plastic sheet over the mattress and ask the guest to supply their own sheets and towels.
Supply a bowl in case of a sick tummy, and plenty of water within easy reach.
I had my hips replaced at 37 and 39 (3 yrs ago )and got haematoma ’ s after both and them things bleed, had to be readmitted but then needed to wear a mechanical devise to remove any excess blood/fluid ( sorry folks) for a month post operative.
Kinda sad, they are on their own.